Elavil IBS Medication

Elavil Medication for Treatment of IBS

Elavil is a tricyclic anti-depressant used in treatment of IBS (Irratable Bowel Syndrome). Since coming off patent, brand name Elavil is no longer available but is manufactured as a generic (amitriptyline hydrochloride). Companies currently manufacturing Elavil include Mylan Pharmaceuticals, Sandoz, Pliva, and Mutual Pharmaceuticals. Tricyclic anti-depressants such as Elavil are anticholenergic-they work by blocking the activity of the nerves responsible for gut motion. Antidepressants help IBS symptoms by affecting the uptake of serotonin, which is a neurotransmitter in the brain involved in the development of clinical depression. The gut's nervous system is rich with nerves containing serotonin. The gut contains 95% of the serotonin in the body, with the remainder in the brain. Blocking the nerve activity responsible for the gut's motion helps reduce diarrhea symptoms of IBS.

Elavil for IBS is given at much lower doses than if used to treat depression. IBS sufferers who have primarily constipation symptoms may find relief with SSRI antidepressants such as Prozac, Celexa, Paxil, and Zoloft, which stimulate serotonin production. Those suffering with diarrhea should avoid SSRI antidepressants, as it may worsen thier symptoms. SSRI (selective seoatonin reuptake inhibitors) affect how the serotonin is reabsorbed. It is crucial that the doctor prescribing Elavil or any other antidepressant for IBS be familiar with its use and possible side effects. Patients may experience an increase in pain, diarrhea, and constipation among other side effects. Other drugs used to treat IBS include anti-spasmodics such as Levsin and Donnatol.

They are taken 30 minutes before meals to reduce the colon's motor activity. For diarrhea, anti-diarrheals such as Imodium and Lomotil may be used. Lomotil should be used with caution as it is chemically related to narcotics and can be habit-forming, with a potential for fatal overdose. Options for treating IBS are limited and require a period of trial and error. The use of soluble fiber, peppermint, fennel, and an IBS diet are often used in conjuction with pharmacotherapy to control symptoms.